Colchicine May Lessen Early AF Recurrences

According to a new study that was published online October 3, 2012 in the Journal of the American College of Cardiology, giving colchicine to AF patients who have undergone pulmonary vein isolation can help to prevent early AF recurrences.

Research has shown that the reduction in the AF recurrences is caused by the lower amount of inflammation that occurs after having a radiofrequency catheter-ablation procedure done. One of the most significant reductions in inflammatory mediators occurs in the interleukin-6 (IL-6) and C-reactive protein (CRP).

The lead researcher in this study, Dr. Georgios Giannopoulos of the Athens General Hospital in Greece, says, “The idea of fighting inflammation after ablation treatment for atrial fibrillation is not a novelty, however, there is the question of how to reduce inflammation. Corticosteroids and [nonsteroidal anti-inflammatory drugs] NSAIDs are out of the question for prolonged use. Colchicine, on the other hand — a low-cost medicine that has been around for more than 2000 years — possesses a unique combination of features: anti-inflammatory action, antiproliferative action and no adverse effects on the cardiovascular system, at least in the dose range used in this study.”

With colchicine providing so much anti-inflammatory action, it should be noted that it can be given without the patient suffering from any major side effects to the heart for long stretches of time. One drug that is often used to treat AF is Multaq, which is made by Sanofi-Aventis. Research has shown that Multaq is not safe for use since it causes liver failure and a worsening of the heart condition for some patients. These side effects are why Multaq has been recommended for use only should all other medications fail to work.

If you or a loved one has suffered from liver failure or a worsening heart condition after being treated with Multaq, contact the attorneys at Greg Jones today for a free consultation. I am experienced at fighting Multaq lawsuits and may be able to help you recover money for your injuries.

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